β 1 integrin function in vivo: Adhesion, migration and more

@article{Brakebusch20051I,
  title={β 1 integrin function in vivo: Adhesion, migration and more},
  author={C. Brakebusch and R. F{\"a}ssler},
  journal={Cancer and Metastasis Reviews},
  year={2005},
  volume={24},
  pages={403-411}
}
  • C. Brakebusch, R. Fässler
  • Published 2005
  • Biology, Medicine
  • Cancer and Metastasis Reviews
  • Adhesion of cells to the surrounding extracellular matrix and to other cells is essential for tissue integrity. In addition to this structural function, cell adhesion induces intracellular signaling mechanisms that regulate proliferation, apoptosis, cell polarity, differentiation and other processes. Cell attachment is mediated by specific receptors that can be grouped into various superfamilies based on structural similarities. Integrins are a family of heterodimeric transmembrane receptors… CONTINUE READING
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