βγ-Dehydrocurvularin and Related Compounds as Nematicides of Pratylenchus penetrans from the Fungus Aspergillus sp.

@article{Kusano2003DehydrocurvularinAR,
  title={$\beta$$\gamma$-Dehydrocurvularin and Related Compounds as Nematicides of Pratylenchus penetrans from the Fungus Aspergillus sp.},
  author={M. Kusano and Kazumi Nakagami and S. Fujioka and T. Kawano and A. Shimada and Y. Kimura},
  journal={Bioscience, Biotechnology, and Biochemistry},
  year={2003},
  volume={67},
  pages={1413 - 1416}
}
The new nematicidal compound, βγ-dehydrocurvularin (1), together with three known compounds, αβ-dehydrocurvularin (2), 8-β-hydroxy-7-oxocurvularin (3) and 7-oxocurvularin (4), were isolated from the culture filtrate and mycelial mats of Aspergillus sp. The structures of 1-4 were established by spectroscopic methods including 2D NMR. The biological activities of 1-4 were examined by bioassays with root-lesion nematodes, and lettuce and rice seedlings. 
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