α5GABAA receptors regulate hippocampal sharp wave-ripple activity in vitro.

Abstract

Sharp waves and ripples (SWRs) are a basic endogenous network activity of the hippocampus. Growing evidence from in vivo studies suggests that this activity plays a crucial role in the process of memory consolidation. Generation of SWR activity requires an intricate interaction between pyramidal cells and specific classes of GABAergic interneurons. Though… (More)
DOI: 10.1016/j.neuropharm.2010.11.022

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