α-spectrin is required for germline cell division and differentiation in the Drosophila ovary

@inproceedings{Cuevas1996spectrinIR,
  title={α-spectrin is required for germline cell division and differentiation in the Drosophila ovary},
  author={M. C. de las Cuevas and John K. Lee and Allan C Spradling},
  year={1996}
}
During Drosophila oogenesis, developing germline cysts are spanned by a large cytoplasmic structure called a fusome, containing α-spectrin and the adducin-like product of the hu-li tai shao (hts) gene. We found that fusomes contain two additional membrane skeletal proteins: β-spectrin and ankyrin. hts was shown previously to be required for cyst formation and oocyte differentiation; the role of the fusome itself, however, and the organization and function of its other components, remains… CONTINUE READING