α-Tocopheryl succinate pre-treatment attenuates quinone toxicity in prostate cancer PC3 cells.

Abstract

UNLABELLED α-Tocopheryl succinate is one of the most effective analogues of vitamin E for inhibiting cell proliferation and inducing cell death in a variety of cancerous cell lines while sparing normal cells or tissues. αTocopheryl succinate inhibits oxidative phosphorylation at the level of mitochondrial complexes I and II, thus enhancing reactive oxygen… (More)
DOI: 10.1016/j.gene.2014.02.009

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