α-Pheromone-Induced “Shmooing” and Gene Regulation Require White-Opaque Switching during Candida albicans Mating

@article{Lockhart2003PheromoneInducedA,
  title={$\alpha$-Pheromone-Induced “Shmooing” and Gene Regulation Require White-Opaque Switching during Candida albicans Mating},
  author={Shawn R. Lockhart and Rui Zhao and Karla J. Daniels and David R Soll},
  journal={Eukaryotic Cell},
  year={2003},
  volume={2},
  pages={847 - 855}
}
ABSTRACT A 14-mer α-pheromone peptide of Candida albicans was chemically synthesized and used to analyze the role of white-opaque switching in the mating process. The α-pheromone peptide blocked cell multiplication and induced “shmooing” in a/a cells expressing the opaque-phase phenotype but not in a/a cells expressing the white-phase phenotype. The α-pheromone peptide induced these effects at 25°C but not at 37°C. An analysis of mating-associated gene expression revealed several categories of… 
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TLDR
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