α-Hydroxyketone Synthesis and Sensing by Legionella and Vibrio

Abstract

Bacteria synthesize and sense low molecular weight signaling molecules, termed autoinducers, to measure their population density and community complexity. One class of autoinducers, the α-hydroxyketones (AHKs), is produced and detected by the water-borne opportunistic pathogens Legionella pneumophila and Vibrio cholerae, which cause Legionnaires' disease… (More)
DOI: 10.3390/s120302899

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