α-Glucosidase inhibitory monoacylated polyhydroxytriterpenoids from the fruits of Barringtonia racemosa

@article{Ponnapalli2015GlucosidaseIM,
  title={$\alpha$-Glucosidase inhibitory monoacylated polyhydroxytriterpenoids from the fruits of Barringtonia racemosa},
  author={Mangala Gowri Ponnapalli and Sushma Sukki and Suresh Annam and Madhu Ankireddy and Harini Tirunagari and Venugopal Raju Tuniki and V. V. Pardhasaradhi Bobbili},
  journal={Tetrahedron Letters},
  year={2015},
  volume={56},
  pages={1570-1574}
}
Acylated flavonoid glycosides from Barringtonia racemosa
TLDR
Three new acylated flavonoid glycosides, namely barringosides G–I (1–3), were isolated from the water-soluble extract of Barringtonia racemosa branches and leaves and showed moderate inhibitory effects on LPS-induced NO production in RAW264.
α‐Glucosidase Inhibitory Monoacylated Polyhydroxytriterpenoids from the Fruits of Barringtonia racemosa.
Monoacylated polyhydroxy triterpenoids racemosol C (I) and racemosol D (II) encountered in this study are unusual and exhibit excellent α-glucosidase inhibition and moderate cytotoxicity.
Triterpenoids.
TLDR
This review covers the isolation and structure determination of triterpenoids reported during 2015 including squalene derivatives, lanostane derivatives, holostanes, cycloartanes, cucurbitanes, dammaranes, euphanes, tirucallanes, tetranortriterpenoids, quassinoids, lupanes, oleananes, friedelanes, ursanes, hopanes, serratanes, isomalabaricanes and saponins.
Int J Biochem Physiol 2018, 3(5): 000141
TLDR
The result of this study revealed that the dichloromethane crude extract of Barringtonia racemosa could be utilized as an agent source of type 2 anti-diabetes.

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TLDR
Two new isomeric acylated oleanane-type triterpenoids along with three known compounds were isolated from the MeOH extract of the dried fruits of Barringtonia racemosa and were not active against HeLa and P388 D1 carcinoma cell lines.
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Nine new acylated triterpenoid saponins (4-12) were isolated from the stem bark of Foetidia africana. They all possess barringtogenol C as the aglycone, esterified by acetic and/or isovaleric acids.
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TLDR
An ethanolic extract of the roots of Barringtonia racemosa afforded two novel neo-clerodane-type diterpenoids, methyl-15 and dimethyl-15, 16-epoxy-12-oxo-3, 13-olide-17-carboxylate, which were determined by NMR and MS analyses and by comparison of their spectral data with related compunds.
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Two major saponins have been isolated from a methanol extract of the seeds of Barringtonia asiatica, and their structures elucidated (mainly by two-dimensional NMR spectroscopy) as
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TLDR
Two new triterpenoid saponins, petersaponins III and IV (1 and 2), were isolated from an n-butanol extract of the bark of Petersianthus macrocarpus and elucidated by extensive NMR experiments.
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TLDR
Compounds 2 and 4 have been identified for the first time in Quercus species and are new compounds.
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TLDR
Four new isomeric macrolides of combretastatin D-2 congeners named isocorniculatolide A, 11-O-methylisocorno-methylcornicULatolides A, and 12-hydroxy-11- O-methyl cornicul atolide B are isolated from the CHCl(3) extract of the bark of Aegiceras corniculatum.
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Nine triterpene saponins, acutangulosides A-F (2-7), and acutanguloside D-F methyl esters (5a-7a) and a single triterpene aglycone (1) were isolated from a water extract of the bark of Barringtonia
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