αβ T cell receptors come out swinging.

@article{Turner2011TC,
  title={αβ T cell receptors come out swinging.},
  author={Stephen John Turner and Jamie Rossjohn},
  journal={Immunity},
  year={2011},
  volume={35 5},
  pages={660-2}
}
It is unclear how an effective T cell repertoire is built from a limited array of T cell receptor (TCR) genes. In this issue of Immunity, Stadinski et al. (2011) demonstrate that TCR variable (V) α chains can indirectly affect Vβ-mediated recognition of the major histocompatibility complex (MHC) molecule.