İdrar interlökin-13, CD80, CD28, matriks metaloproteinaz-2 ve granzim B‘nin çocukluk çağı minimal değişim nefrotik sendrom patogenezindeki rolleri

@article{Zeybek2014drarIC,
  title={İdrar interl{\"o}kin-13, CD80, CD28, matriks metaloproteinaz-2 ve granzim B‘nin çocukluk çağı minimal değişim nefrotik sendrom patogenezindeki rolleri},
  author={Cengiz Zeybek and Duygu {\"O}vunc Hacihamdioglu and S. Yavuz and A. Pekel and C. Akg{\"u}n and B. Bulum and K. Gulleroglu and A. Kantar and A. Kavaz and U. Muşabak and F. Yalçınkaya and E. Baskın and F. Gok},
  journal={Journal of Clinical and Experimental Investigations},
  year={2014},
  volume={5},
  pages={354-361}
}
  • Cengiz Zeybek, Duygu Övunc Hacihamdioglu, +10 authors F. Gok
  • Published 2014
  • Medicine
  • Journal of Clinical and Experimental Investigations
  • Objective: Minimal change disease (MCD) is the most common cause of nephrotic syndrome in childhood but its pathogenesis remains poorly understood. A T-cell-derived factor or factors were initially alleged as contributing to the disease pathogenesis. However, podocyte CD80 expression is now a commonly discussed theory. The aim of this study was to investigate the pathogenesis of MCD by determining urine interleukin-13, CD80, CD28, matrix metalloproteinase-2 (MMP-2), and granzyme B levels… CONTINUE READING
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