Über humorale Übertragbarkeit der Herznervenwirkung

  title={{\"U}ber humorale {\"U}bertragbarkeit der Herznervenwirkung},
  author={Otto Loewi and Ernst Navratil},
  journal={Pfl{\"u}ger's Archiv f{\"u}r die gesamte Physiologie des Menschen und der Tiere},
  • O. LoewiE. Navratil
  • Published 1 December 1926
  • Chemistry
  • Pflüger's Archiv für die gesamte Physiologie des Menschen und der Tiere

Loss of Cholinergic Receptor Muscarinic 1 (CHRM1) Protein in the Hippocampus and Temporal Cortex of a Subset of Individuals with Alzheimer's Disease, Parkinson's Disease, or Frontotemporal Dementia: Implications for Patient Survival.

Severe reduction of CHRM1 in a subset of AD and PD patients can explain the reported low efficacy of AChE inhibitors as a mitigating treatment for dementia patients.


The Mouse Brainstem (Truncus encephali)

The mammalian brainstem is composed in caudocranial order of the medulla oblongata, the pons, and the midbrain (mesencephalon), and the main difference to the spinal cord is the endowment of the brainstem with nuclei, fiber tracts, and nerves for the innervation of the head-specific organs.

Exploring the Pathogenesis of Alzheimer Disease in Basal Forebrain Cholinergic Neurons: Converging Insights From Alternative Hypotheses

Current attempts to prevent and/or treat AD are addressed in light of advances in understanding pathogenetic mechanisms and it is suggested that studies in the DS population may provide unique insights into AD pathogenesis and treatment.

A Novel Antiserum Against a Predicted Human Peripheral Choline Acetyltransferase (hpChAT) for Labeling Neuronal Structures in Human Colon

The present results demonstrate the specificity and reliability of the hpChAT antiserum as a novel tool for immunohistochemical studies in human colon, opening venues to map cholinergic innervation in other human PNS tissues.