Über dieAnhalonium-Alkaloide

  title={{\"U}ber dieAnhalonium-Alkaloide},
  author={E. Sp{\"a}th},
  journal={Monatshefte f{\"u}r Chemie und verwandte Teile anderer Wissenschaften},
  • E. Späth
  • Monatshefte für Chemie und verwandte Teile anderer Wissenschaften

Psychedelic Drugs

This chapter reviews preclinical and clinical research involving indolalkylamines, arylcyclohexamines, and substituted amphetamines, for which LSD, PCP, and MDMA are used as the prototypes, respectively.

Receptor Interaction Profiles of 4-Alkoxy-Substituted 2,5-Dimethoxyphenethylamines and Related Amphetamines

4-alkyloxy-substituted 2,5-dimethoxyamphetamines and Phenethylamines share some trends with the many other phenethylamine pharmacophore containing compounds, such as when increasing the size of the 4- substituent and increasing the lipophilicity, the affinities at the 5-HT2A/C subtype also increase, and only weak 5- HT2A or C subtype selectivities were achieved.

The fourfold discovery of Mescaline (1896–1919)

  • Ivo Gurschler
  • Chemistry
    Monatshefte für Chemie - Chemical Monthly
  • 2019
This is an historical account of the pharmacological, chemical, and anthropological research concerning the molecular makeup of the peyote cactus (Lophophora williamsii) that laid the ground for

100 years of mescaline

  • M. Jay
  • Psychology
    Monatshefte für Chemie - Chemical Monthly
  • 2019
In the hundred years since Ernst Späth’s synthesis of mescaline, it has been used in clinical research for many purposes, including the study of hallucinations, creativity, and schizophrenia. After

Alkaloids of the Cactaceae — The Classics

  • B. Cassels
  • Chemistry
    Natural Product Communications
  • 2019
Some recorded activities of the 1,2,3,4-tetrahydroisoquinoline alkaloids suggests a need for additional studies, especially in connection with their co-administration with mescaline, as in dried cacti and in beverages prepared from them.

Pharmacokinetic And Pharmacodynamic Aspects Of Peyote And Mescaline: Clinical And Forensic Repercussions.

It is clear that most intoxications appear to be mild and are unlikely to produce life-threatening symptoms, which favors the contemporary interest in the therapeutic potential of the drugs of the class.

The DARK Side of Total Synthesis: Strategies and Tactics in Psychoactive Drug Production.

This targeted review provides brief historical accounts of the main classes of psychoactive drugs and discusses several foundational total syntheses that ultimately provide the groundwork for producing these molecules in academic, industrial, and clandestine settings.

Unifying Theories of Psychedelic Drug Effects

Making an explicit effort to investigate the principles and mechanisms of psychedelic drug effects is a uniquely powerful way to iteratively develop and test unifying theories of brain function.

The History of Psychedelics in Medicine

Psychedelics have been used for hundreds if not thousands of years by humans. Medical research began in earnest in theWest in the late nineteenth century with the discovery of mescaline. From there