- MedicineSpringer International Publishing
This chapter provides contemporary information on the historical timeline of events that transpired on GI physiology beginning from antiquity to the contemporary period to allow for meaningful future investigations that could fetch the world results for the betterment of life.
Étude fonctionnelle de l'AMP-activated protein kinase chez l'huître creuse Crassostrea gigas
L’objectif de cette these etait de caracteriser les elements appartenant a la voie de signalisation energetique AMP-activated protein kinase chez l’huitre creuse Crassostrea gigas afin de comprendre…
A history of research on yeasts 5: the fermentation pathway
- Biology, ChemistryYeast
The results confirmed the existence of an identical glycolytic pathway in yeasts, animals and plants and the role of NAD and NADP in fermentation.
Mitochondrial Impairment: A Common Motif in Neuropsychiatric Presentation? The Link to the Tryptophan–Kynurenine Metabolic System
- Biology, PsychologyCells
The functions of mitochondria and the Trp-KYN system, the interaction of the Tr p–kynurenine system with mitochondria, and the current understanding of the involvement of mitochondrial functions and the tryptophan-kyN system in preclinical and clinical studies of major neurological and psychiatric diseases are discussed.
Luciferase-Based Determination of ATP/NAD(H) Pools in a Marine (Environmental) Bacterium
- Biology, Environmental ScienceMicrobial Physiology
Methods for luciferase-based determination of ATP/NAD(H) pools open a promising approach to investigate energy and redox states in marine (environmental) bacteria.
The legacy of A. V. Hill's Nobel Prize winning work on muscle energetics
- BiologyThe Journal of physiology
V. V. Hill pioneered the integration of mathematics into the study of physiology and pharmacology and his work on muscle energetics was extended after 1922, as a result of Hill's own work and that of others, to the present day.
A novel definition and treatment of hyperinflammation in COVID-19 based on purinergic signalling
- Biology, MedicinePurinergic signalling
The readily available and affordable P2X7R antagonist lidocaine can abrogate hyperinflammation and restore the normal immune function in critically ill COVID-19 patients treated with lidocane.
Glycolysis: How a 300yr long research journey that started with the desire to improve alcoholic beverages kept revolutionizing biochemistry
- Current Opinion in Systems Biology
The therapeutic potential of inorganic polyphosphate: A versatile physiological polymer to control coronavirus disease (COVID-19)
This review summarizes the state of the art of the biotherapeutic potential of the polymer polyP and the findings from basic research and outlines future biomedical applications.
That was then, this is now: the development of our knowledge and understanding of P2 receptor subtypes
- BiologyPurinergic signalling
Deep insight into the molecular mechanisms of agonist and antagonist action has been provided by more recent determination of the tertiary and quaternary structures of several P2X and P2Y receptor subtypes.