Über die Pyrophosphatfraktion im Muskel

  title={{\"U}ber die Pyrophosphatfraktion im Muskel},
  author={Davenport U. Sacks},
Gastrointestinal Physiology
Curiosity and the quest for addressing human maladies or problems of nature are possibly the key driving forces for discoveries in science. Apart from shaping the reputation of the scientists andExpand
Étude fonctionnelle de l'AMP-activated protein kinase chez l'huître creuse Crassostrea gigas
L’objectif de cette these etait de caracteriser les elements appartenant a la voie de signalisation energetique AMP-activated protein kinase chez l’huitre creuse Crassostrea gigas afin de comprendreExpand
A history of research on yeasts 5: the fermentation pathway
The results confirmed the existence of an identical glycolytic pathway in yeasts, animals and plants and the role of NAD and NADP in fermentation. Expand
That was then, this is now: the development of our knowledge and understanding of P2 receptor subtypes
Deep insight into the molecular mechanisms of agonist and antagonist action has been provided by more recent determination of the tertiary and quaternary structures of several P2X and P2Y receptor subtypes. Expand
The P2Y/P2X divide: how it began.
  • C. Kennedy
  • Biology, Medicine
  • Biochemical pharmacology
  • 2021
High resolution imaging of the tertiary and quaternary structures of several P2X and P2Y receptor subtypes has provided a much greater understanding of how and where agonists and antagonists bind to the receptors and how this leads to changes in receptor conformation and activity. Expand
The therapeutic potential of inorganic polyphosphate: A versatile physiological polymer to control coronavirus disease (COVID-19)
This review summarizes the state of the art of the biotherapeutic potential of the polymer polyP and the findings from basic research and outlines future biomedical applications. Expand
In Memoriam Geoffrey Burnstock: Creator of Purinergic Signaling
Geoff Burnstock (1929–2020) discovered purinergic signaling in a fastidious research that started in early 1960 and culminated in a concept of purinergic nerves in 1972. Subsequently, GeoffExpand
Mitochondrial lactate metabolism: history and implications for exercise and disease
It is argued that lactate is not directly oxidized in the mitochondrial matrix, and the interim glycolytic products (pyruvate and NADH) are held in cytosolic equilibrium with the products of the lactate dehydrogenase (LDH) reaction and the intermediates of the malate‐aspartate and glycerol 3‐phosphate shuttles. Expand
Splitting aptamers and nucleic acid enzymes for the development of advanced biosensors
Functional nucleic acid assemblies that are derived from aptamers and ribozymes/DNAzymes are reviewed, focusing on the thrombin, the adenosine/ATP and the cocaine split aptamer as the three most studied DNA split systems and on split DNAzyme assemblies. Expand
Subchronic (90-Day) repeated dose toxicity study of disodium adenosine-5'-triphosphate in rats.
Subchronic administration of ATP was well tolerated at all dose levels and the no-observed-adverse-effect level (NOAEL) was determined to be ≥ 2000 mg kg BW-1·d-1, which was the highest dose tested. Expand