Celebrating 75 years of oestradiol.
- Medicine, BiologyJournal of molecular endocrinology
The history of the discovery of oestrogens, the mechanisms of their synthesis, and their therapeutic applications are very important components of the fabric of endocrinology and the rationale for highlighting several key components of this story is provided.
Advances in the Care of Transgender Children and Adolescents.
- MedicineAdvances in pediatrics
Estrogens and female developing brain: two sides of the coin
- BiologyREPRODUCTIVE ENDOCRINOLOGY
It was concluded that in the early stages of female life, estrogens play a different role in the programming of the neuroendocrine system and behavior, depending on the period of individual development.
In Silico Prediction of Steroids and Triterpenoids as Potential Regulators of Lipid Metabolism
- MedicineMarine drugs
This review focuses on a rare group of steroids and triterpenoids that share common properties as regulators of lipid metabolism and related processes such as anti-hyperlipoproteinemic activity, as well as the treatment of atherosclerosis, lipoprotein disorders, or inhibitors of cholesterol synthesis.
Membrane-initiated actions of sex steroids and reproductive behavior: A historical account
- MedicineMolecular and Cellular Endocrinology
Estrogen and thrombosis: A bench to bedside review.
- MedicineThrombosis research
Nuclear Hormone Receptors and Their Ligands: Metabolites in Control of Transcription
- Biology, MedicineCells
This review makes a brief historical journey from the first observations by Berthold in 1849 to the era of orphan receptors that began with the sequencing of the Caenorhabditis elegans genome in 1998 and defines four classes of metabolites—fatty acids, terpenoids, porphyrins and amino acid derivatives—that generate all known ligands for nuclear hormone receptors.
Role of nuclear and membrane estrogen signaling pathways in the male and female reproductive tract.
- Medicine, BiologyDifferentiation; research in biological diversity
The human testes: Estrogen and ageing outlooks
ENDOCRINE HISTORY: The history of discovery, synthesis and development of testosterone for clinical use.
- MedicineEuropean journal of endocrinology
Over 85 years the testosterone preparations have been slowly improved so that now physiological serum levels can be achieved and testosterone has been available for clinical use.