Étude génétique du rétinoblastome


A genetic study of 598 patients with retinoblastoma was made-10.5% were familial, 36% had the bilateral form. The data confirmed that these two forms differ in their mode of inheritance; the bilateral are due to a germinal dominant mutation, whereas the unilateral are due in most cases to a somatic mutation and are therefore non-hereditary. The recurrence… (More)
DOI: 10.1007/BF00297591