• Corpus ID: 73822255

Étude de cas Mise en évidence d'une soumission chimique à la niaprazine chez des enfants par analyse des cheveux en CL-SM/SM Determination of niaprazine-facilitated sedation in children by hair analysis with LC-MS/MS

@inproceedings{Villain2008tudeDC,
  title={{\'E}tude de cas Mise en {\'e}vidence d'une soumission chimique {\`a} la niaprazine chez des enfants par analyse des cheveux en CL-SM/SM Determination of niaprazine-facilitated sedation in children by hair analysis with LC-MS/MS},
  author={Marion Villain and Emilie Vallet and Vincent Cirimele and Pascal Kintz},
  year={2008}
}

• M. Villain, E. Vallet, +1 author P. Kintz
• Published 2008
• Psychology

Niaprazine, under the trade name Nopron, is largely used in France as an hypnotic agent for occasional insomnia of children. This compound is available without medical prescription. The first case involving repetitive administration of niaprazine as a drug-facilitated sexual assault is reported. Three children (2 girls and 1 boy) were repetitively sedated and assaulted by their father-in-law between 2002 and 2006. Niaprazine's liquid formulation rep- resents a good potential access to surreptitiously administer it in beverages. According to the request of the judge in charge of this case, hairs of victims were collected, segmented and screened for sedatives by LC-MS/MS. Niaprazine was detected in the range 21 to 3431 pg/mg for the three children. These concentrations could not be compared with previous results, due to a lack of literature.