Corpus ID: 12774039

[miR-21 promotes pulmonary fibrosis in rats via down-regulating the expression of ADAMTS-1].

@article{Liu2016miR21PP,
  title={[miR-21 promotes pulmonary fibrosis in rats via down-regulating the expression of ADAMTS-1].},
  author={Lijing Liu and Huiming Yin and Minjiang Huang and Jianbin He and Gaozhong Yi and Zaiyan Wang and H. Qian},
  journal={Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology},
  year={2016},
  volume={32 12},
  pages={
          1636-1640
        }
}

Lijing Liu, Huiming Yin, +4 authors H. Qian

Published 2016

Medicine

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology

Objective To observe the effect of miR-21 on bleomycin-induced pulmonary fibrosis in rats, and explore the related mechanism. Methods Peripheral blood was collected from idiopathic pulmonary fibrosis (IPF) patients (n=20) and healthy adults (n=20). Fluorescence quantitative real-time PCR was then used to measure miR-21 expression. Forty-five SD rats were randomly divided into control group, miR-21 agomir group and miR-21 antagomir group. Each group included 15 rats. After establishment of… CONTINUE READING

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