[mechanisms of Modulation of Reflex Control of Breathing at Elevated Systemic Level of Proinflammatory Cytokine Interleukin-1β].

@article{Aleksandrova2015mechanismsOM,
  title={[mechanisms of Modulation of Reflex Control of Breathing at Elevated Systemic Level of Proinflammatory Cytokine Interleukin-1β].},
  author={Nina P Aleksandrova and V A Merkuriev and T. S. Tumanova and Viacheslav G Aleksandrov},
  journal={Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova},
  year={2015},
  volume={101 10},
  pages={1158-68}
}
This study explores the hypothesis about the possible involvement of the cyclooxygenase pathway in the effects of interleukin-1beta (IL-1β) on the breathing pattern and Heuring-Breuer respiratory reflexes. Respiratory frequency (fR), tidal volume (VT) and esophageal pressure were recorded in 29 adult male Wistar rats anaesthetized with urethane. Heuring-Breuer reflexes were tested by airway occlusion at achieving functional residual capacity (inspiratory-inhibitory reflex), and at the height of… CONTINUE READING