[beta-Endorphin enhances IL-2 and IFN-gamma gene expression in human blood mononuclear cells].

@article{Lin1997betaEndorphinEI,
  title={[beta-Endorphin enhances IL-2 and IFN-gamma gene expression in human blood mononuclear cells].},
  author={Jeng Feng Lin and Yu-fei Shen and Yang Gao and Long-Yun Li},
  journal={Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae},
  year={1997},
  volume={19 5},
  pages={
          353-6
        }
}
The effect of beta-endorphin (beta-END) stimulation of cytokines production by PHA-induced human peripheral blood mononuclear cells (PBMC) was studied by reverse transcription in combination with polymerase chain reaction (RT/PCR), slot blotting and hybridization to detect and measure messenger RNA (mRNA). beta-END significantly and dose dependently enhanced IFN-gamma and IL-2 mRNA expression of T cells and naloxone (Nal) reversed the effect of beta-END on IL-2 mRNA expression. The results… CONTINUE READING