[Water uptake of tablets, their disintegration and dissolution are in close relation].


Authors investigated the factors influencing this connection on phenylbutazone tablets. Tablets were prepared by wet granulation using three binders (gelatine, hydroxypropyl-cellulose, hydroxyethylcellulose) in different concentrations. Three disintegrants were compared (polyvinylpolypyrrolidon, formalin-casein and cyclodextrin polymer) on the basis of… (More)


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