[Vonoprazan: a novel potassium-competitive acid blocker].

  title={[Vonoprazan: a novel potassium-competitive acid blocker].},
  author={Kentaro Sugano},
  journal={Nihon rinsho. Japanese journal of clinical medicine},
  volume={73 7},
  • Kentaro Sugano
  • Published 2015 in
    Nihon rinsho. Japanese journal of clinical…
A potent, rapid acting potassium-competitive acid blocker, vonoprazan, is introduced for clinical use in Japan. A number of phase III clinical trials comparing the efficacy of vonoprazan with lansoprazole, showed non-inferior or superior effectiveness in a spectrum of acid-related diseases. In particular, vonoprazan was superior to regular dose of lansoprazole in healing severe gastroesophageal reflux diseases (Los Angeles grade C and D). A triple therapy regimen with vonoprazan, amoxicillin… CONTINUE READING

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