Corpus ID: 2731108

[Vitamin E inhibits homocysteine-mediated smooth muscle cell proliferation].

@article{Zou2007VitaminEI,
  title={[Vitamin E inhibits homocysteine-mediated smooth muscle cell proliferation].},
  author={T. Zou and N. Liu and Shu-De Li and Yong-chun Su and Y. Man and D. Lu},
  journal={Nan fang yi ke da xue xue bao = Journal of Southern Medical University},
  year={2007},
  volume={27 6},
  pages={
          783-6
        }
}

T. Zou, N. Liu, +3 authors D. Lu

Published 2007

Biology, Medicine

Nan fang yi ke da xue xue bao = Journal of Southern Medical University

OBJECTIVE To investigate the role of reactive oxygen species (ROS) and the effect of vitamin E on proliferation of vascular smooth muscle cells (VSMCs) induced by homocysteine. METHODS DNA synthesis in the VSMCs cells was measured using [3H]-thymidine incorporation assay, and the cell number determined by trypan blue method. The level of ROS in the cells was determined using DCF-DA as the fluorescence probe. RESULTS Homocysteine promoted VSMC DNA synthesis, proliferation, and ROS production… CONTINUE READING

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