[Visfatin upregulates MMP-2 and MMP-9 expressions in human monocytes through activating NF-kappaB].

@article{Huang2010VisfatinUM,
  title={[Visfatin upregulates MMP-2 and MMP-9 expressions in human monocytes through activating NF-kappaB].},
  author={Fen Huang and Xiao-fang Xiong and Sha You and Qiong-xin Wang and He-song Zeng},
  journal={Zhonghua xin xue guan bing za zhi},
  year={2010},
  volume={38 5},
  pages={455-9}
}
OBJECTIVE To investigate the effects of visfatin on the MMP-2 and MMP-9 expressions in human monocytes and related mechanisms. METHODS Human monocytes were isolated from blood, the expressions of MMP-2 and MMP-9 at mRNA and protein levels were detected in visfatin stimulated monocytes (0, 100, 200, 400 ng/ml) in the absence and presence of NF-kappaB inhibitor specific Bay11-7082 by Realtime PCR or Western blot, the MMP-2 and MMP-9 enzyme activity in the culture media was also detected by… CONTINUE READING

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