[Vasodilator actions of felodipine, a new Ca2+ entry blocker].

  title={[Vasodilator actions of felodipine, a new Ca2+ entry blocker].},
  author={M. Kawakami and K. Bian and N. Toda},
  journal={Nihon yakurigaku zasshi. Folia pharmacologica Japonica},
  volume={94 4},
Felodipine [ethylmethyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5- pyridinedicarboxylate], a new Ca2+ entry blocker, relaxed isolated canine arteries and veins precontracted with prostaglandin (PG) F2 alpha, in a concentration-dependent manner. Felodipine dilated cerebral arteries predominantly over the other arteries. Relaxations by felodipine, in low concentrations, were greater in mesenteric vein strips than in mesenteric artery strips isolated from the same dogs. The inhibitory… Expand
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