[Value of protein 53 expression in lymphoma. Its correlation with genetic mutations].

@article{Echezarreta1997ValueOP,
  title={[Value of protein 53 expression in lymphoma. Its correlation with genetic mutations].},
  author={G Echezarreta and Badeia Marcos and Cristina Sanz and Beatriz Larru Martinez and Javier Ben{\'i}tez and Harold Oliva and Carmen Sanchez de Rivas},
  journal={Sangre},
  year={1997},
  volume={42 5},
  pages={369-75}
}
PURPOSE p53 is a tumour suppressor gene encoding a nuclear phosphoprotein that plays an important role in the control of normal cell proliferation. We have tried to establish the value of expression of the p53 protein in malignant lymphomas and its correlation with the presence of structural gene abnormalities. MATERIAL AND METHODS 230 cases of lymphomas (11 Hodgkin's disease and 219 non-Hodgkin's) were studied by immunohistochemistry using an anti-p53 monoclonal antibody (DO-7, DAKO… CONTINUE READING