[Value of promoter methylation of RASSF1A, p16, and DAPK genes in induced sputum in diagnosing lung cancers].

@article{Peng2010ValueOP,
  title={[Value of promoter methylation of RASSF1A, p16, and DAPK genes in induced sputum in diagnosing lung cancers].},
  author={Zai-mei Peng and Changting Shan and Huifang Wang},
  journal={Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences},
  year={2010},
  volume={35 3},
  pages={247-53}
}
OBJECTIVE To determine the aberrant methylation status of RASSF1A,p16 and DAPK gene promoter region in induced sputum from lung cancer patients and the value of their combined detection in diagnosing lung cancers. METHODS Methylation-specific PCR (MSP) was used to detect the promoter methylation status of RASSF1A, p16, and DAPK genes in induced sputum and pathological tissues from 82 patients with lung cancers and 25 patients with pulmonary benign lesion. We also analyzed the relation between… CONTINUE READING
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