Corpus ID: 45645921

[Tumor suppressor gene PTEN and non-alcoholic steatohepatitis (NASH)].

  title={[Tumor suppressor gene PTEN and non-alcoholic steatohepatitis (NASH)].},
  author={Wataru Sato and Yasuo Horie and Sumio Watanabe and Akira John Suzuki},
  journal={Nihon rinsho. Japanese journal of clinical medicine},
  volume={63 8},
  • Wataru Sato, Yasuo Horie, +1 author Akira John Suzuki
  • Published in
    Nihon rinsho. Japanese…
  • Medicine
  • Although hepatic steatosis had been considered to be a benign condition that does not deteriorate to either liver cirrhosis or hepatocellular carcinoma (HCC). Non-alcoholic steatohepatitis (NASH) is notable disease that has similar pathological features to alcoholic liver injury and progresses to liver cirrhosis and HCC. But the molecular mechanism for the onset of NASH, and for the transformation from steatosis to carcinogenesis are still unclear. Hepatocyte-specific PTEN deficient mice, we… CONTINUE READING

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