[Treatment of metastatic malignant melanoma with interleukin-2].

  title={[Treatment of metastatic malignant melanoma with interleukin-2].},
  author={Thierry Dorval and Wolf Herman Fridman and Claire Mathiot and Xavier Sastre and Pierre Pouillart},
  journal={Bulletin du cancer},
  volume={79 8},
Between April 1988 and December 1990, 37 patients with progressive histologically proven metastatic melanoma were treated with interleukin-2 according to three multicentric successive protocols. Eighteen males and 19 females entered the trial. Mean age was 44 years (range 20-66); none of the patients had severe visceral disease or brain metastasis. Superficial and visceral metastatic sites were equally distributed. Interleukin-2 was administered as a 3 to 5 day continuous intravenous infusion… CONTINUE READING