[Treatment of homozygous familial hypercholesterolemia with LDL-apheresis on a 4-year-old child].

@article{Lefort2009TreatmentOH,
  title={[Treatment of homozygous familial hypercholesterolemia with LDL-apheresis on a 4-year-old child].},
  author={Bruno Lefort and C Giraud and J-P Saulnier and Lucile Bott and Catherine Gambert and P Sosner and R{\'e}gis Hankard},
  journal={Archives de pediatrie : organe officiel de la Societe francaise de pediatrie},
  year={2009},
  volume={16 12},
  pages={1554-8}
}
Homozygous familial hypercholesterolemia (HFH) is a rare genetic disease associated with increased atherosclerosis, resulting in premature death near the age of 20 years. Treatment requires the LDL-apheresis system. M, born from a consanguineous union, suffers from HFH (total-cholesterol=12.29 g/l, LDL-cholesterol=9.65 g/l). Diet and drug treatment was not associated with decreased LDL-cholesterol. At the age of 4.5 years (body weight: 16.7 kg), M began treatment with LDL-apheresis. Apheresis… CONTINUE READING