[Treatment of hairy cell leukemia with cladribine].

  title={[Treatment of hairy cell leukemia with cladribine].},
  author={Igor Aurer and Zdravko Mitrovi{\'c} and Jasminka Kovacevi{\'c}-Metelko and Ivo Radman and Sandra Ba{\vs}i{\'c}-Kinda and Koraljka Gjadrov-Kuve{\vz}di{\'c} and Jasminka Jaki{\'c}-Razumovi{\'c} and Klara Dubrav{\vc}i{\'c} and Sun{\vc}ica Ries and Marin Nola and Silva Zupan{\vc}i{\'c}-{\vS}alek and Boris Labar},
  journal={Lijecnicki vjesnik},
  volume={129 3-4},
Hairy cell leukemia is a chronic B-cell lymphoproliferative disorder characterized by clonal proliferation of hairy cells. Treatments of choice are purine analogues, particularly cladribine. We treated thirty patients with cladribine either by continuous 7-day infusion at a daily dose of 0.1 mg/kg or by 2-h infusion for 5 consecutive days at a daily dose of 0.14 mg/kg. Remission was achieved in 90% of the patients. After a median follow-up of 44 months overall survival is 93% and time to… CONTINUE READING