Corpus ID: 24608506

[Total flavonoids of litsea coreana decreases the cytotoxicity of oxaliplatin in TM3 Leydig cells via enhancing the function of gap junction].

@article{Yu2014TotalFO,
  title={[Total flavonoids of litsea coreana decreases the cytotoxicity of oxaliplatin in TM3 Leydig cells via enhancing the function of gap junction].},
  author={Bin-bin Yu and X. Tong and Shu-ying Dong and Yuchen Gu and Hao Jiao and J. Ji and Biao Qu},
  journal={Zhonghua nan ke xue = National journal of andrology},
  year={2014},
  volume={20 5},
  pages={
          400-4
        }
}
  • Bin-bin Yu, X. Tong, +4 authors Biao Qu
  • Published 2014
  • Chemistry, Medicine
  • Zhonghua nan ke xue = National journal of andrology
OBJECTIVE To investigate the effects of total flavonoids of Litsea Coreana (TFLC) on the gap junction (GJ) intercellular communication in TM3 testicular Leydig cells and whether TFLC can reduce the cytotoxicity of oxaliplatin (OHP) in vitro. METHODS We detected the effect of TFLC on the dye spread of the in vitro cultured TM3 cells by parachute assay, observed changes in the expression of connexin 43 (Cx43) total protein in the TFLC-treated TM3 cells by Western blot, and determined the… Expand