[Toll-like receptor 8: the awkward TLR].

@article{Alexopoulou2012TolllikeR8,
  title={[Toll-like receptor 8: the awkward TLR].},
  author={Lena Alexopoulou and Benoit Desnues and Olivier Demaria},
  journal={Medecine sciences : M/S},
  year={2012},
  volume={28 1},
  pages={
          96-102
        }
}
Toll-like receptors (TLR) sense a variety of microbial products and play an important role in the mounting of innate and adaptive immune responses. TLR1 to TLR9 are common in mice and humans and recognize similar ligands in both species, with the exception of TLR8. Human TLR7 and TLR8 and mouse TLR7 detect viral single-stranded RNA and imidazoquinoline compounds, while mouse TLR8 not. Based on this discrepancy, for long time it was believed that mouse TLR8 is not functional and as a consequence… 
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