[Tofacitinib for the treatment of rheumatoid arthritis].

  title={[Tofacitinib for the treatment of rheumatoid arthritis].},
  author={Yoshiya Tanaka},
  journal={Nihon rinsho. Japanese journal of clinical medicine},
  volume={74 6},
  • Yoshiya Tanaka
  • Published 2016 in
    Nihon rinsho. Japanese journal of clinical…
The combined use of synthetic disease-modifying anti-rheumatic drugs (sDMARDs) such as methotrexate and biological DMARDs (bDMARDs) has revolutionized treatment of rheumatoid arthritis (RA). Remission is now realistic targets, achieved by a large proportion of RA patients. However, bDMARDs are limited to intravenous or subcutaneous uses and orally available small but strong products have been developed. Oral administration of tofacitinib targeting the Janus kinase (JAK) is significantly… CONTINUE READING

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