[Therapy of cognitive deficits in schizophrenia with acetylcholinesterase inhibitors. A systematic overview].

@article{Voss2008TherapyOC,
  title={[Therapy of cognitive deficits in schizophrenia with acetylcholinesterase inhibitors. A systematic overview].},
  author={Bianca Voss and Renate Thienel and Stefan Leucht and T. Kircher},
  journal={Der Nervenarzt},
  year={2008},
  volume={79 1},
  pages={
          47-8, 50-2, 54-9
        }
}
Patients with schizophrenia suffer from cognitive deficits which are important predictors of functional outcome. Alterations such as reduced muscarinic and nicotinic receptors in the central cholinergic system in patients with schizophrenia may contribute to these cognitive impairments. Because such deficits do not respond to neuroleptic treatment, different approaches have been developed regarding pharmacological treatments that enhance central cholinergic transmission, e.g. with… CONTINUE READING