Corpus ID: 46554533

[Therapeutic efficacy of novel 17alpha-hydroxyprogesterone derivatives in experimental preterm labor].

@article{Tapilskaia2002TherapeuticEO,
  title={[Therapeutic efficacy of novel 17alpha-hydroxyprogesterone derivatives in experimental preterm labor].},
  author={N. I. Tapil'skaia and M. A. Petrosian and E. Lesik},
  journal={Eksperimental'naia i klinicheskaia farmakologiia},
  year={2002},
  volume={65 1},
  pages={
          44-5
        }
}
The ability of a series of new 17 alpha-Hydroxyprogesteron derivatives (acetomepregnol, AMOL phenyl propyoate, butagest) in preventing the prostaglandin-induced preterm labor was experimentally studied in mice. It was found that all the synthetic gestagens studied, especially butagest, maintained pregnancy in all test animals on the model of enzaprost F induced abortion. The proposed progestogens can be used to prevent abortion in pregnancies in cases of risk from diseases connected with excess… Expand