[The synthesis and immunosuppressive effects of steroid-peptide linkers].

Abstract

Hydrocortisone was coupled with urotoxin tripeptide UTP-A, UTP-B and UTP-C respectively yielding 4 linkers. Their bioactivities such as prolongation of heterotopic transplanted cardiac tissue survival, inhibitory effects on phagocytosis of mouse peritoneal macrophages and the influence on Con A induced proliferation of spleen lymphocytes of mouse were… (More)

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Cite this paper

@article{Wang1998TheSA, title={[The synthesis and immunosuppressive effects of steroid-peptide linkers].}, author={C. Wang and S. Peng and Xiaolong Zhang and Xiao Qiu}, journal={Yao xue xue bao = Acta pharmaceutica Sinica}, year={1998}, volume={33 2}, pages={111-6} }