[The structure and antiviral activity of ribavirin analogs. II. Molecular and crystal structure of 1-(1,5-dihydroxy-3-oxapent-2-yl)-1,2,4-triazole-5-carboxamide].

@article{Tsapkina1988TheSA,
  title={[The structure and antiviral activity of ribavirin analogs. II. Molecular and crystal structure of 1-(1,5-dihydroxy-3-oxapent-2-yl)-1,2,4-triazole-5-carboxamide].},
  author={E N Tsapkina and G V Gurskaia and S. G. Zavgorodnii and S V Lindeman and Iu T Struchkov},
  journal={Bioorganicheskaia khimiia},
  year={1988},
  volume={14 8},
  pages={1092-7}
}
X-ray structure of the title compound, an antiviral agent moderately active towards Herpes simplex virus type 1, has been determined. The space group is P2i/n, unit cell parameters: a = 10,119, b = 7,529, c = 13,585 A, beta = 107,82 degrees, Z = 4. The structure was solved by the direct method and refined by least-squares procedure to R = 2.9%. The gauche… CONTINUE READING