[The specific killing of human melanoma cells by replication selective adenovirus].

@article{Xie2003TheSK,
  title={[The specific killing of human melanoma cells by replication selective adenovirus].},
  author={Qing-jun Xie and Ying-Lin Lu and Ze-jian Chen and Jin-qiang Zhang and Hui-hua Chen and Xian-long Ling and Pin L{\"u} and Zhi-yan Du and Yuan-ji Xu},
  journal={Zhonghua zhong liu za zhi [Chinese journal of oncology]},
  year={2003},
  volume={25 5},
  pages={448-52}
}
OBJECTIVE To construct replication selective adenovirus AdhepE1 targeting human melanoma and observe its specific killing of human melanoma cells in vitro. METHODS Adenovirus E1 region, the murine tyrosinase promoter and enhancer DNA sequences were acquired respectively by PCR cloning. The shuttle plasmid of replication-selective adenovirus targeting… CONTINUE READING