[The sodium-iodide symporter. Pathophysiologic, diagnostic and therapeutic significance].

@article{Spitzweg2003TheSS,
  title={[The sodium-iodide symporter. Pathophysiologic, diagnostic and therapeutic significance].},
  author={Christine Spitzweg},
  journal={Der Internist},
  year={2003},
  volume={44 4},
  pages={396-402, 404-8, 410-1}
}
The sodium iodide symporter NIS) is an intrinsic plasma membrane protein that mediates the active transport of iodide in the thyroid gland and a number of extrathyrioidal tissues, in particular lactating mammary gland. Because of its crucial role in the ability of thyroid follicular cells to trap iodide of NIS opened an exciting and extensivenew field of thyroid-related research. Cloning and molecular characterization of NIS allowed investigation of its expression and regulation in thyroidal… CONTINUE READING