[The significance of circulating microparticles in physiology, inflammatory and thrombotic diseases].

@article{Morel2005TheSO,
  title={[The significance of circulating microparticles in physiology, inflammatory and thrombotic diseases].},
  author={Olivier Morel and Nicolas Morel and B{\'e}n{\'e}dicte Hugel and Laurence Jesel and St{\'e}phane Vinzio and Bernard Goichot and Bab{\'e} Bakouboula and Leila Grunebaum and J M Freyssinet and Florence Toti},
  journal={La Revue de medecine interne},
  year={2005},
  volume={26 10},
  pages={791-801}
}
BACKGROUND In multicellular organisms, apoptosis and subsequent microparticle shedding play a key role in homeostasis. Having long been considered as << cellular dust >>, microparticles released in biological fluids upon cell activation or apoptosis appear as multifunctional bioeffectors involved in the modulation of key functions including immunity, inflammation, hemostasis and thrombosis, angiogenesis. MP constitute reliable markers of vascular damage, accessible to biological detection… CONTINUE READING