Corpus ID: 29550457

[The semisynthetic production of pharmacologically active flavone derivatives. I. The pharmaco-toxicological properties of theophylline-rutozide (TR 1722)].

@article{Danila1990TheSP,
  title={[The semisynthetic production of pharmacologically active flavone derivatives. I. The pharmaco-toxicological properties of theophylline-rutozide (TR 1722)].},
  author={G. Danila and Mihai Nechifor},
  journal={Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi},
  year={1990},
  volume={94 1},
  pages={
          151-6
        }
}
  • G. Danila, M. Nechifor
  • Published 1990
  • Medicine
  • Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi
The pharmaco-toxicological properties of the compound theophylline-rutozide, termed conventionally TR-1722, are presented. Studied comparatively with aminophylline, it presents important advantages: soluble in water, the aqueous solutions have a pH close to the physiological one and are stable. It induces a weaker excitation on the central nervous system as compared to aminophylline, but its antihistaminic and anti-inflammatory properties are slightly increased. The physicochemical and… Expand