[The role of opioidergic and GABAergic systems in the mechanosensitivity regulation of the respiratory system in rats].

@article{Tikhomirova2015TheRO,
  title={[The role of opioidergic and GABAergic systems in the mechanosensitivity regulation of the respiratory system in rats].},
  author={L. N. Tikhomirova and N. F. Safina and Ilya Alekseyevich Tarakanov},
  journal={Patologicheskaia fiziologiia i eksperimental'naia terapiia},
  year={2015},
  volume={59 4},
  pages={
          26-9
        }
}
In anaesthetized white outbred male rats we investigated the change of respiratory mechanoreceptors sensitivity to morphine and phenibut. Bilateral transection of the vagus nerves causes a severely slowdown of respiratory rate in 30 minutes after the systemic administration of morphine, however after administration of phenibut the respiratory rate and other respiration parameters have not changed significantly. It means that the activation of opioid receptors by morphine does not significantly… CONTINUE READING