[The role of endothelium and nitric oxide in the regulation of vascular tone].

@article{Puzserova2008TheRO,
  title={[The role of endothelium and nitric oxide in the regulation of vascular tone].},
  author={Angelika Puzserova and Jana Kopincov{\'a} and Iveta Bernatova},
  journal={Ceskoslovenska fysiologie},
  year={2008},
  volume={57 2-3},
  pages={53-60}
}
Vascular system is a large complex of tubes with different diameters which are able to perceive changes of endogenous milieu, to integrate and modulate signals of intercellular communication and to respond and adapt by a local production of different kinds of mediators affecting vascular structure and function. For a long time, it has been assumed that the main determinant of vasomotor function was the nervous system and the monolayer of endothelial cells was only a physical barrier between the… CONTINUE READING