[The role of blockage of various M-cholinoreceptor subtypes in induction of tachycardia in rats].

Abstract

The mechanism of the effect of M-cholinoblockers on the heart rate was analysed. It is suggested on the basis of this analysis that tachycardia induced in reats by muscarinic antagonists was caused by blockade of ther central M1-cholinoceptors which is accompanied with increase in the tone of the sympathetic branch of the autonomic nervous system. 

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