[The role of SDF-1/CXCR4 on airway inflammation and airway remodeling in a rat asthma model].

Abstract

OBJECTIVE To explore the roles of stromal cell-derived factor 1 (SDF-1) and C-X-C chemokine receptor 4 (CXCR4) on airway inflammation and airway remodeling in rat asthma models. METHODS Eighteen female SD rats were randomly divided into 3 groups (n = 6): control group, asthmatic 4 weeks group and asthmatic 8 weeks group. The rats were sensitized and… (More)

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