[The relationship between the plasma homocysteine level and the polymorphism of MTHFR gene C667T in liver cirrhosis].

@article{Zhou2005TheRB,
  title={[The relationship between the plasma homocysteine level and the polymorphism of MTHFR gene C667T in liver cirrhosis].},
  author={Xiu-min Zhou and Ju-sheng Lin and Xue-mei Sun and Wang-xian Tang and Wen-ying Zhang and Shun-yu Yuan and Li Ai},
  journal={Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology},
  year={2005},
  volume={13 12},
  pages={908-10}
}
OBJECTIVE To study the relationship between the plasma homocysteine (HCY) level and the polymorphism of N(5), N(10)-methylenetetrahydrofolate reductase (MTHFR) gene C667T in liver cirrhosis. METHODS 112 normal subjects and 87 liver cirrhosis patients were recruited in the study. Their plasma HCY levels were measured using high performance liquid chromatography with fluorescence detection and polymorphisms of their MTHFR gene were analyzed using PCR-RFLP. RESULTS The mean level of plasma HCY… CONTINUE READING