[The regulation of steroidogenesis by 17 alpha-hydroxylase/17,20-lyase (P450c17)].

Abstract

Cytochrome P450c17 (P450c17) catalyzes 17 alpha-hydroxylation and 17, 20-lyase reactions. This enzyme plays a key role in determination of the balance between glucocorticoids and steroid sex hormones. In this review we discuss recent progress in the studies of both transcriptional regulation of CYP17 encoding P450c17 and enzymatic regulation of P450c17… (More)

Topics

Cite this paper

@article{Katagiri1998TheRO, title={[The regulation of steroidogenesis by 17 alpha-hydroxylase/17,20-lyase (P450c17)].}, author={Masatoshi Katagiri and Naoki Kagawa}, journal={Nihon yakurigaku zasshi. Folia pharmacologica Japonica}, year={1998}, volume={112 1}, pages={43-50} }