[The primary study on the anti-HBV effect of whole recombinant yeast].

@article{Zeng2003ThePS,
  title={[The primary study on the anti-HBV effect of whole recombinant yeast].},
  author={Yan Zeng and Da-chuan Cai and Mingli Peng and H Ren},
  journal={Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology},
  year={2003},
  volume={11 12},
  pages={728-30}
}
OBJECTIVES Based on the immunologic character of Pichia pastoris yeast, a new therapeutic vaccine, whole recombinant yeast, was used to explore a new way to activate cell-mediated anti-viral immunity. METHODS The recombinant plasmids, pPIC9K/S and PIC9K/hsp(1-370)-S, were constructed by inserting the gene encoding HBsAg, HSP70 (1-370) -HBsAg into vector… CONTINUE READING