[The phenomenon of antigenic defectiveness in naturally circulating strains of the tick-borne encephalitis virus and its possible connection to seronegative forms of the disease].

@article{Pogodina1992ThePO,
  title={[The phenomenon of antigenic defectiveness in naturally circulating strains of the tick-borne encephalitis virus and its possible connection to seronegative forms of the disease].},
  author={Vanda V. Pogodina and Nadezshda G. Bochkova and Tatiana I Dzhivanian and Ludmila S. Levina and Galina G. Karganova and R A Riasova and V A Sergeeva and Vasilii A Lashkevich},
  journal={Voprosy virusologii},
  year={1992},
  volume={37 2},
  pages={103-7}
}
Ten strains of tick-borne encephalitis (TBE) virus isolated from single specimens of I. persulcatus ticks were studied. The strains were divided into antigenically complete (AC) and antigenically defective (AD), depending on the presence or absence of some virus antigens in concentrated virus preparations, characteristics in rocket immune electrophoresis (RIEP), rate and intensity of humoral immune response in monkeys and rabbits, and plaque size in SPEV cell culture. The AC-strain markers… CONTINUE READING