[The mechanism of thermo-induced functional uncoupling of the Ca-pump in the sarcoplasmic reticulum of skeletal muscles].

@article{Boldyrev1986TheMO,
  title={[The mechanism of thermo-induced functional uncoupling of the Ca-pump in the sarcoplasmic reticulum of skeletal muscles].},
  author={Alexander A. Boldyrev and Peter J. Quinn and Volodymyr I. Lushchak},
  journal={Biokhimiia},
  year={1986},
  volume={51 1},
  pages={150-9}
}
Short-term heating at 45 degrees C of diluted suspensions of rabbit skeletal muscle sarcoplasmic reticulum (SR) vesicles sharply reduces the Ca/ATP ratio without causing any appreciable changes in the Ca-ATPase activity. The mechanism underlying the uncoupling effect of thermoinactivation was investigated. It was shown that the decrease in the effectiveness… CONTINUE READING